glp-1 colitis Engineered probiotic restores signaling to ameliorate fiber-deficiency exacerbated Ulcerative colitis and GLP-1 medications

Although elevated homocysteine has the potential to be neurotoxic to dopaminergic neurons which in turn may cause depressive symptoms (Bhatia and Singh, 2015) the overall effect of lowering homocysteine over the course of two years by supplementation with vitamin B12, folate and vitamin D3 was not seen to make a significant difference to the reduction of depressive symptoms in a randomised control trial with older adult participants (De Koning et al, 2016)

Clin Case Rep 2017;5:160811

This, in turn, reduces the levels of nuclear receptor coactivator 4, which helps to suppress ferroptosis/iron autophagy in chondrocytes

Shen, C